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Supports Healthy Adrenal Gland Function and Manages Fatigue*
Adrenaplex™ contains key nutrients essential for healthy adrenal gland function with highly absorbable freeze-dried Adrenal Extract, L-Tyrosine, Licorice Extract, Vitamin C, and many other important adrenal supporting nutrients which help revitalize the adrenal gland.
The adrenal glands help the body fight against stress and fatigue, and are responsible for controlling stress hormones, cortisol and adrenaline. People who display adrenal insufficiency can experience the following characteristics. They may go to bed early but awaken at midnight or after and can’t fall back to sleep. They crave salt or sugar and generally are exhausted after physical or verbal confrontation and after exercising. They are intolerant to heat or neutral about cold or hot. People with weak adrenals complain of fatigue 94% of the time; premenstrual tension 85%; inability to concentrate 77%; craving for sweets 75%; allergies 73%; apprehension 71%; headaches 68%; alcohol intolerance 66%; mental and muscular weakness 65%; pain in the neck and trapezius muscles 65%; confusion 61%; poor memory 59%; heart palpitations 57%; backache 48%; light-headedness 47%; constipation or diarrhea 45%; faintness or fainting spells 42%; insomnia 40%; skin blemishes 39%; compulsive behavior 38%. Some of the physical signs they may display are low blood pressure 93%, dry or thin skin 91%, scanty perspiration 91%, low basil metabolic rate 85%, sparse hair on body 83%, underweight 78%.*
How It Works
The adrenal gland requires intake of specific nutrients in order to maintain healthy secretion of key hormones involved with the body’s stress response, including adrenaline and cortisone. Additional supportive nutrients for energy and stress resistance make Adrenaplex an excellent daily supplement to revitalize the adrenal gland and improve the body’s response to stress.*
Adrenal glands are rich in vitamin C. During stressful events, they secrete this antioxidant vitamin which may act as protection against oxidative stress.*1
DHEA is a hormone synthesized in the adrenal glands. Supplementation with DHEA has been shown to improve energy and vitality, especially in women who need extra adrenal support. *2-4
The amino acid L-tyrosine helps the body resist the negative effects of stress. *5
Licorice prevents the breakdown of adrenal hormones, making them more available to the body. *6
Pregnenolone is a natural hormone produced by the adrenal glands. It is a precursor (building block) for other hormones such as DHEA.*7
Vitamin B6 (Pyridoxal-5-phosphate)
Pyridoxal-5-phosphate plays a role in the formation of neurotransmitters, including serotonin and dopamine, which play a role in mood and emotion. *9
Glandular ingredients from animal sources, such as adrenal extract, contain naturally occurring hormones and nutrients which can support human glandular function. *8
Pantothenic acid Pantothenic acid plays an important role in cellular energy production and in the metabolism of energy from fats. *10
Rehmannia root extract was used in Traditional Chinese Medicine as a tonic, and to increase energy. This herb contains a compound called catalpol which helps stimulate production of adrenal hormones. It has been noted to aid in regulating the activity of the adrenal cortex by promoting the function of the hypothalamus-pituitary-adrenal axis and the release of steroid hormones.*11,12
The adrenal glands are actually two glands in one. Sitting on top of each kidney, the inner gland is known as the adrenal medulla, while the outer gland is the adrenal cortex. The medulla produces adrenalin. The cortex produces cortisone. The function of the adrenal gland is crucial to how our bodies respond to stress, as the hormones it secretes are what cause the physical changes needed to respond to emergency situations. However, a high-stress life can leave the adrenal glands in need of extra support and nutrition.*
Recommendations: 1 to 2 capsules daily or as desired.
Serving Size: 2 Capsules
Servings Per Container: 30 Amount/Serving Daily Value
Vitamin C 200 mg 333%
Pregnenolone 15 mg **
DHEA 10 mg **
Adrenal Extract 450 mg **
(Freeze dried adrenal powder)
L-Tyrosine 450mg **
Licorice (Glycyrrhiza glabra) Root (5:1) Extract 125 mg **
(Freeze dried adrenal powder)
P5P (Pyridoxal-5-phosphate) 10 mg **
Pantothenic Acid (Calcium Pantothenate) 100 mg 1000%
Rehmannia (Rehmannia glutinosa) Root (5:1) Extract 75 mg **
**Daily Value Not Established.
Other Ingredients: gelatin, cellulose, vegetable source magnesium stearate, silicon dioxide
Contains no: sugar, salt, soy, yeast, wheat, gluten, corn, dairy products, artificial coloring, artificial flavoring or preservatives.
If pregnant or nursing, consult a health care practitioner before using.
Made in the USA.
1. Padayatty SJ, Doppman JL, Chang R, Human adrenal glands secrete vitamin C in response to adrenocorticotrophic hormone. Am J Clin Nutr. 2007;86(1):145-9.
2. Allolio B, Arlt W, Hahner S. DHEA: why, when, and how much--DHEA replacement in adrenal insufficiency. Ann Endocrinol (Paris). 2007;68(4):268-73.
3. Johannsson G, Burman P, Wirén L, et al. Low dose dehydroepiandrosterone affects behavior in hypopituitary androgen-deficient women: a placebo-controlled trial. J Clin Endocrinol Metab. 2002;87(5):2046-52.
4. Binder G, Weber S, Ehrismann M, et al. Effects of dehydroepiandrosterone therapy on pubic hair growth and psychological well-being in adolescent girls and young women with central adrenal insufficiency: a double-blind, randomized, placebo-controlled phase III trial. J Clin Endocrinol Metab. 2009;94(4):1182-90.
5. Deijen JB, Orlebeke JF. Effect of tyrosine on cognitive function and blood pressure under stress. Brain Res Bull. 1994;33(3):319-23
6. Isbrucker RA, Burdock GA. Risk and safety assessment on the consumption of Licorice root (Glycyrrhiza sp.), its extract and powder as a food ingredient, with emphasis on the pharmacology and toxicology of glycyrrhizin. Regul Toxicol Pharmacol. 2006c;46(3):167-92.
7. Soucy P, Luu-The V. Conversion of pregnenolone to DHEA by human 17alpha-hydroxylase/17, 20-lyase (P450c17). Evidence that DHEA is produced from the released intermediate, 17alpha-hydroxypregnenolone. Eur J Biochem. 2000;267(11):3243-7
8. Glandulars. In: Hendler SS, ed. PDR for Nutritional Supplements. 2nd ed. Montvale, NJ: Physician’s Desk Reference; 2008:264.
9. Vitamin B6. In: In: Hendler SS, ed. PDR for Nutritional Supplements. 2nd ed. Montvale, NJ: Physician’s Desk Reference; 2008:634-644
10. Coombs G. Pantothenic Acid. In: The Vitamins: Fundamental Aspects in Nutrition and Health. San Diego, California: Academic Press, Inc; 1992:345-356.
11. Dharmananda S. Rehmannia. Available at: http://www.itmonline.org/arts/rehmann.htm. Accessed on December 3, 2009.
12. Blood tonics. In: Reid DP. Chinese Herbal Medicine. Boston, Mass: Shambala Publications; 1992:150.
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Terry Lemerond, Founder & President, has 40 years experience in the health food industry having owned several health food stores and nutritional manufacturing companies. He has researched and developed over 300 nutritional and botanical formulations that continue to be top selling products on the market today. He is credited to be the first to introduce to the U.S. health food market glucosamine sulfate, IP6, black cohosh for menopause, the concept of botanical standardization and the introduction of complex formulations for specific health indications.
View his articles, Terry Talks Nutrition.
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